3-[3-(1,1'-biphenyl)-4-yl-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzopyran-2-one

3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxycoumarin

C₃₁H₂₄O₃

Formar Buff/beige polvo.

Punto de fusion 215-217℃.

Solubilidad en water 31×10^-3 (pH 5.2), 2.5 (pH 7.3), 84 (pH 9.3) (all en mg/l, 20℃). Slightly soluble en alcohols. en acetone, chloroFormar >50, ethyl acetate 2, benzene 0.6 (all en g/l, 25℃).

Agudo agudo oral LD50 para male rats 1.8, female rats 2.45, male mice 0.8, rabbits 2.0, female guinea pigs 50, dogs >50, cats >100, pigs >50 mg/kg. Sub-acute oral LD50 (5 d) para male rats 0.16 mg/kg/day. Piel y ojos agudos percutaneous LD50 para male rats 27.4, female rats 17.2, rabbits 1000 mg/kg. Non-Irritante para la piel y ojos(rabbits). no a skin sensitiser (guinea pigs).

Effective against rats and most mice resistant to other anticoagulants.